Stats

Aggregate Data From Connected Scales Shows Minimal Weight Gains During Lockdowns (expressnews.com) 55

"Data from connected scale users suggests Americans, on average, are not gaining weight during lockdowns," writes long-time Slashdot reader pfhlick.

The Washington Post reports: Withings, the maker of popular Internet-connected scales and other body-measurement devices, studied what happened to the weight of some 450,000 of its American users between March 22 — when New York ordered people home — and April 18. Despite concerns about gaining a "quarantine 15," the average user gained 0.21 pounds during that month... Over the same March-April period in 2019, Withings said its American users gained slightly less weight — 0.19 pounds on average — though fewer people had the scales last year...

Dariush Mozaffarian, dean of the School of Nutrition Science and Policy at Tufts University — who wasn't involved with the Withings analysis — said he found the results a bit disappointing. "With the shutdown of the restaurants, I thought the numbers would have gotten better," he said. Home-cooked meals tend to be healthier than dining out.

Withings' numbers varied slightly for other countires. But citing a professor of medicine at Stanford, the article notes that average weight gains may be misleading, since some people "may be hitting their groove during stay-at-home orders by embracing cooking and taking up jogging. But others could be using food to cope with stress and gaining large amounts of weight." In fact, 37% of the scale owners gained more than a pound. (Which, if my math is correct, suggests that the other 63% had to lose at least .13 pounds.)

The article also notes that for buyers of Withings' scales, "contributing aggregate data is a condition included in its terms of service; its customers don't get the option to opt out if they want to use Withings products."
Medicine

Bill Gates Complains America's Coronavirus Testing Data is 'Bogus' (businessinsider.com) 185

Appearing on CNN Thursday, Bill Gates called America's coronavirus testing data "bogus," in part because "the United States does not make sure you get results in 24 hours." Business Insider reports: Testing in the U.S. remains a long and complicated task, and it can take several days before people are told whether they have tested positive or negative for COVID-19. "If you get your test results within 24 hours so you can act on it, then let's count it," Gates said, adding that people were most infectious within the first three to four days after infection and might continue to interact with others and spread the virus until they have definitive results. "What's the point of the test?" he said. "That's your period of greatest infectiousness."

Gates added that residents of low-income neighborhoods had lesser access to testing facilities and were not prioritized, despite indications that the virus has taken a disproportionate toll on marginalized communities. "Our system fails to have the prioritization that would give us an accurate picture of what's going on," he said.

While America is now testing about 200,000 people a day, the article cites experts from Harvard University who believe 20 million tests a day are what's needed to fully "remobilize the economy."
NASA

NASA Names Companies To Develop Human Landers For Artemis Moon Missions (nasa.gov) 39

New submitter penandpaper shares an excerpt from a NASA press release: NASA has selected three U.S. companies to design and develop human landing systems (HLS) for the agency's Artemis program, one of which will land the first woman and next man on the surface of the Moon by 2024. NASA is on track for sustainable human exploration of the Moon for the first time in history. The human landing system awards under the Next Space Technologies for Exploration Partnerships (NextSTEP-2) Appendix H Broad Agency Announcement (BAA) are firm-fixed price, milestone-based contracts. The total combined value for all awarded contracts is $967 million for the 10-month base period. The following companies were selected to design and build human landing systems:

- Blue Origin of Kent, Washington, is developing the Integrated Lander Vehicle (ILV) -- a three-stage lander to be launched on its own New Glenn Rocket System and ULA Vulcan launch system.
- Dynetics (a Leidos company) of Huntsville, Alabama, is developing the Dynetics Human Landing System (DHLS) -- a single structure providing the ascent and descent capabilities that will launch on the ULA Vulcan launch system.
- SpaceX of Hawthorne, California, is developing the Starship -- a fully integrated lander that will use the SpaceX Super Heavy rocket.
"With these contract awards, America is moving forward with the final step needed to land astronauts on the Moon by 2024, including the incredible moment when we will see the first woman set foot on the lunar surface," said NASA Administrator Jim Bridenstine. "This is the first time since the Apollo era that NASA has direct funding for a human landing system, and now we have companies on contract to do the work for the Artemis program."

Further reading: SpaceX and NASA Break Down What Their Historic First Astronaut Mission Will Look Like
United Kingdom

Robert May, Former UK Chief Scientist and Chaos Theory Pioneer, Dies Aged 84 (theguardian.com) 11

Pioneering Australian scientist Robert May, whose work in biology led to the development of chaos theory, has died at age 84. The Guardian reports: Known as one of Australia's most accomplished scientists, he served as the chief scientific adviser to the United Kingdom, was president of the Royal Society, and was made a lord in 2001. Born in Sydney on January 8, 1938, May's work was influential in biology, zoology, epidemiology, physics and public policy. More recently, he applied scientific principles to economics and modeled the cause of the 2008 global financial crisis. On Wednesday, his friends and colleagues paid tribute to a man who they said was a gifted polymath and a "true giant" among scientists.

Dr Benjamin Pope, an Australian astrophysicist and student at Oxford from 2013 to 2017, said May was a role model, and meeting him was a highlight of his university career. "I became aware of his achievements almost as soon as I learnt anything about physics in university," Pope told Guardian Australia. "My first contact with computer programming was at the University of Sydney, in first year physics, where the example is to recreate Robert May's experiment with the bifurcation diagram and the logistic map. "His bifurcation diagram is one of the iconic diagrams in physics," he said. "[And] he made what was between three or four independent discoveries that lead to chaos theory. You might have heard of the butterfly effect ... May's is probably the other foundational, computational model of chaos."

Transportation

'Hydrogen-On-Tap' Device Turns Trucks Into Fuel-Efficient Vehicles (ieee.org) 148

An anonymous reader quotes a report from IEEE Spectrum: The city of Carmel, Ind., has trucks for plowing snow, salting streets, and carrying landscaping equipment. But one cherry-red pickup can do something no other vehicle can: produce its own hydrogen. A 45-kilogram metal box sits in the bed of the work truck. When a driver starts the engine, the device automatically begins concocting the colorless, odorless gas, which feeds into the engine's intake manifold. This prevents the truck from guzzling gasoline until the hydrogen supply runs out. The pickup has no fuel cell module, a standard component in most hydrogen vehicles. No high-pressure storage tanks or refueling pumps are needed, either.

Instead, the "hydrogen-on-tap" device contains six stainless steel canisters. Each contains a 113-gram button of an aluminum and gallium alloy. A small amount of water drips onto the buttons, causing a chemical reaction that splits the oxygen and hydrogen contained in the water. The hydrogen releases, and the rest turns into aluminum oxide, a waste product that can be recycled to create more buttons. Back in the garage, the driver can replace spent canisters with news ones to replenish the hydrogen supply. AlGalCo -- short for Aluminum Gallium Company -- has spent 14 years refining the technology, which is based on a process developed by distinguished engineer Jerry Woodall. In 2013, AlGalCo partnered with the Carmel Street Department to build a prototype for one of the city's Ford F-250 trucks. In tests, the red pickup has seen a 15 percent improvement in gas mileage and a 20 percent drop in carbon dioxide emissions.

Medicine

Dogs Are Now Being Trained To Sniff Out Coronavirus 44

New Slashdot submitter Joe2020 shares a report from the BBC: Firefighters in Corsica, France, are aiming to teach canines how to sniff out coronavirus, as they can other conditions. It's hoped that detection dogs could be used to identify people with the virus at public places like airports. Their trial is one of several experiments being undertaken in countries including the UK and the USA. "Each individual dog can screen up to 250 people per hour," James Logan, head of the London School of Hygiene & Tropical Medicine, told The Washington Post. "We are simultaneously working on a model to scale it up so it can be deployed in other countries at ports of entry, including airports." The dogs are trained using urine and saliva samples collected from patients who tested positive and negative for the disease.

"We don't know that this will be the odor of the virus, per se, or the response to the virus, or a combination," Cynthia Otto, director of the Working Dog Center at Penn's School of Veterinary Medicine, told the publication. "The dogs don't care what the odor is ... What they learn is that there's something different about this sample than there is about that sample."
Space

SpaceX and NASA Break Down What Their Historic First Astronaut Mission Will Look Like (techcrunch.com) 19

NASA and SpaceX's most defining moment of our current space era is coming up at the end of this month, with its Demo-2 mission on May 27. The mission will be the first ever launch for SpaceX with humans on board, and for NASA, it'll mark the first return to U.S.-based astronaut launches since the Shuttle program flew its last flight in 2011. On Friday, representatives from both SpaceX and NASA briefed the media on the mission and the specifics of what it will involve when astronauts Bob Behnken and Doug Hurley board the Crew Dragon for its debut crewed performance. From a report: The first thing to note about this mission is that it's still technically a test, as noted in the "demo" name. This is the capstone demonstration in a series of such missions that will fully human-rate the SpaceX Crew Dragon and Falcon 9 for operational use. As noted during today's press briefings, a big chunk of the actual human rating process occurs during this final mission -- in fact, the majority of the actual final human rating happens on this flight, despite the many years of preparation and live tests to date, including the Demo-1 mission which was essentially a full round-trip flight, just without any astronauts on board. Even though it's technically a demonstration, the stakes couldn't be higher -- SpaceX has a lot to prove here, and it bears the utmost responsibility in terms of keeping Behnken and Hurley safe for the duration of the mission. Which, it turns out, is actually going to be longer than originally planned: NASA says the mission will last anywhere between 30 days and 119 days, depending on a few different factors, the most significant of which being how quickly the agency ends up being able to launch the first operational Commercial Crew mission, Crew-1, which will carry four astronauts, including two from NASA and one from Japan's space agency.
Medicine

Nvidia's Top Scientist Develops Open-source Ventilator That Can Be Built With $400 in Readily Available Parts (techcrunch.com) 48

New submitter jsicolo shares a report: Nvidia Chief Scientist Bill Dally has released an open-source ventilator hardware design he developed in order to address the shortage resulting from the global coronavirus pandemic. The mechanical ventilator design developed by Dally can be assembled quickly, using off-the-shelf parts with a total cost of around $400 -- making it an accessible and affordable alternative to traditional, dedicated ventilators, which can cost $20,000 or more. The design created by Dally strives for simplicity, and basically includes just two central components -- a solenoid valve and a microcontroller. The design is called the OP-Vent, and in this video you can see how bare-bones it is in terms of hardware compared to existing alternatives, including some of the other more complex emergency-use ventilator designs developed in response to COVID-19.
Medicine

Bill Gates Says Virus Vaccine Could Take as Little as 9 Months (bloomberg.com) 98

Bill Gates, whose foundation is focusing its efforts to fight the coronavirus, doesn't think life will return to normal until there's a viable vaccine that can stop its spread. The good news is that it may take less time than many have been predicting. From a report: "Dr. Anthony Fauci has said he thinks it'll take around eighteen months to develop a coronavirus vaccine," Gates wrote in a blog post published Thursday. "I agree with him, though it could be as little as 9 months or as long as two years." Even if it takes 18 months, that would still be the fastest that scientists have created a new vaccine, Gates said, adding that he's thinks eight to ten of the 115 current COVID-19 vaccine candidates look promising. "I'm particularly excited by two new approaches that some of the candidates are taking: RNA and DNA vaccines," he wrote. "It might be a bit hard to see right now, but there is a light at the end of the tunnel."
Earth

The Largest Arctic Ozone Hole Ever Recorded is Now Closed (cbsnews.com) 47

Just as suddenly as it first formed, a record-breaking ozone hole has healed. The largest ozone hole to ever open up over the Arctic is now closed, after first opening up earlier this spring. From a report: Scientists monitoring the "unprecedented" hole at the Copernicus Atmospheric Monitoring Service (CAMS) announced the closure last week. Despite coronavirus lockdowns leading to a significant reduction in air pollution, researchers said the pandemic likely was not the reason for the ozone hole closing. "Actually, COVID19 and the associated lockdowns probably had nothing to do with this," CAMS tweeted Sunday. "It's been driven by an unusually strong and long-lived polar vortex, and isn't related to air quality changes." Now that the intense polar vortex has ended, the ozone hole has closed. CAMS said Monday that it does not expect the same conditions to occur next year.
Medicine

WHO Lauds Lockdown-Ignoring Sweden As a 'Model' For Countries Going Forward (nypost.com) 467

An anonymous reader quotes a report from The New York Post: The World Health Organization lauded Sweden as a "model" for battling the coronavirus as countries lift lockdowns -- after the nation controversially refused restrictions. Dr. Mike Ryan, the WHO's top emergencies expert, said Wednesday there are "lessons to be learned" from the Scandinavian nation, which has largely relied on citizens to self-regulate. "I think there's a perception out that Sweden has not put in control measures and just has allowed the disease to spread," Ryan told reporters. "Nothing can be further from the truth."

Ryan noted that instead of lockdowns, the country has "put in place a very strong public policy around social distancing, around caring and protecting people in long-term care facilities." "What it has done differently is it has very much relied on its relationship with its citizenry and the ability and willingness of its citizens to implement self-distancing and self-regulate," Ryan said. "In that sense, they have implemented public policy through that partnership with the population." He said the country also ramped up testing and had adequate capacity in hospitals to handle any outbreaks. "I think if we are to reach a new normal, Sweden represents a model if we wish to get back to a society in which we don't have lockdowns," Ryan said.
Last month, more than 2,300 Swedish researchers penned a letter demanding the government enact stricter regulations. "Until we get a better idea of the situation, I think it is a good idea to close schools, restaurants and entertainment venues," said Olle Kampe, an immunology researcher at the Karolinska Institute, in March.

"[Sweden], which has a population of 10.3 million, has seen more than 20,300 cases and 2,462 deaths as of Thursday afternoon -- far higher than its Nordic neighbors, which implemented stricter containment measures," the report adds.

UPDATE (5/22/2020): 19 days later, Covid-19 deaths in Sweden "were the highest in Europe per capita in a rolling seven-day average," reports the Guardian, citing data from the scientific online publication Ourworldindata.com. And Sweden's death rate per million (376) was "far in advance of Norway's (44), Denmark's (96) and Finland's (55) — countries with similar welfare systems and demographics, but which imposed strict lockdowns..."
Space

Is Space-Time Quantized Or Analog? (space.com) 148

"What are the implications if 'space-time' (as conceived of in the Einstein Theory of General Relativity) is quantized like all other aspects of matter and energy?" asks Slashdot reader sixoh1. Space.com reports of a new study that tried to find out: In order for the math of general relativity to work, this fabric of space-time has to be absolutely smooth at the tiniest of scales. No matter how far you zoom in, space-time will always be as wrinkle-free as a recently ironed shirt. No holes, no tears, no tangles. Just pure, clean smoothness. Without this smoothness, the mathematics of gravity simply break down. But general relativity isn't the only thing telling us about space-time. We also have quantum mechanics (and its successor, quantum field theory). In the quantum world, everything microscopic is ruled by random chance and probabilities. Particles can appear and disappear at a moment's notice (and usually even less time than that). Fields can wiggle and vibrate with a will all their own. And nothing can ever be known for certain. [...]

That's exactly what a team of astronomers did, submitting their results for publication in the Monthly Notices of the Royal Astronomical Society, and also posting their work to the online preprint site arXiv. And in a perfect coincidence, they searched for the frothiness of space-time using ... espresso. No, not the drink. ESPRESSO, the Echelle Spectrograph for Rocky Exoplanet and Stable Spectroscopic Observations, an instrument based at the European Southern Observatory's Very Large Telescope. As its name suggests, ESPRESSO was not designed to search for space-time frothiness, but it turned out to be the best tool for the job. And the astronomers pointed it at a perfect source: a run-of-the-mill gas cloud sitting over 18 billion light-years away. What makes this particular gas cloud especially useful is two facts. One, there is a bright source sitting just behind it, illuminating it. And two, there's iron in the cloud, which absorbs the background light at a very specific wavelength.

So from our vantage point on Earth, if space-time is perfectly smooth, that gap in the background light caused by the gas cloud should be just as narrow as if the cloud was sitting right next to us. But if space-time is frothy, then the light traveling over the billions of light-years will spread out, changing the width of the gap. The astronomers didn't find any hint of frothiness, which doesn't mean that it doesn't exist -- it just means that if space-time is frothy, we need more than 18 billion light-years to see it with our current technology. But the results were able to rule out some models of quantum gravity, sending them into the proverbial dustbin of physics history.

NASA

FDA Authorizes NASA-Developed Ventilator For Use In COVID-19 Treatment (techcrunch.com) 26

An anonymous reader quotes a report from TechCrunch: The U.S. Food and Drug Administration (FDA) has authorized for emergency use as outlined in the agency's COVID-19 guidelines a new ventilator designed by engineers working at NASA's Jet Propulsion Laboratory. The ventilator, which has an acronym because this is NASA we're talking about, is called "VITAL" (Ventilator Intervention Technology Accessible Locally), and its design is being offered for free, licensed use for the duration of the coronavirus crisis. The JPL-developed emergency use ventilator is an intubation ventilator, meaning that a patient has to be sedated, with a breathing tube inserted all the way down their airway to assist their breathing. It's reserved for COVID-19 patients exhibiting the most serious symptoms, and even then is really designed for use only to free up availability of existing, fully approved ventilator hardware in the case of extreme shortages.

What makes VITAL most interesting is that it is made of "far fewer" parts than existing traditional ventilators, according to NASA, and it also can be assembled much more quickly, and maintained with less expertise and effort over time. The design provides for use for between three or four months, however, rather than years for traditional hardware, and is meant specifically for COVID-19 patient use, hence its simpler design versus models that are made to serve in a number of different medical situations. NASA's JPL is seeking commercial manufacturing partners for the hardware now that it has its authorization, however, in order to get it built in large numbers for distribution to hospitals in need.

Earth

Glowing Blue Waves Lighting Up SoCal Coastline Roll Into the South Bay (latimes.com) 43

Crashing waves emitting a flash of neon blue have lit up darkened stretches of Southern California's coastline this month, most recently making an appearance in the South Bay. From a report: The sporadic phenomenon -- sometimes called sea sparkle -- is something scientists have been studying for 120 years. It's associated with a red tide, or an algae bloom, made up of organisms called dinoflagellates. These tiny single-celled organisms are common members of the coastal plankton community that float on or near the ocean's surface and can emit bioluminescence, most commonly when they're grabbed by a predator. The light acts to startle their attacker, according to Michael Latz, a marine biologist with the Scripps Institution of Oceanography at UC San Diego.

Occasionally, the organisms are found in high concentrations, resulting in red tides and known for giving the ocean water a deep red, brown or orange hue during the day. At night, they can put on a truly spectacular show when jostled by a crashing wave or the wake of a boat. Red tides are difficult to predict, and not all of them produce bioluminescence. Scientists still aren't sure about all the factors that lead to them, Latz said.

Space

Hubble Captures Breakup of Comet ATLAS (phys.org) 20

The Hubble Space Telescope has captured the breakup of Comet ATLAS, a.k.a. C/2019 Y4. "The telescope resolved roughly 30 fragments of the fragile comet on April 20 and 25 pieces on April 23," reports Phys.Org. From the report: The Hubble Space Telescope's new observations of the comet's breakup on April 20 and 23 reveal that the broken fragments are all enveloped in a sunlight-swept tail of cometary dust. These images provide further evidence that comet fragmentation is probably common and might even be the dominant mechanism by which the solid, icy nuclei of comets die. [...] Because comet fragmentation happens quickly and unpredictably, reliable observations are rare. Therefore, astronomers remain largely uncertain about the cause of fragmentation. One suggestion is that the original nucleus spins itself into pieces because of the jet action of outgassing from sublimating ices. As this venting is likely not evenly dispersed across the comet, it enhances the breakup. [...] Hubble's crisp images may yield new clues to the breakup. The telescope has distinguished pieces as small as the size of a house. Before the breakup, the entire nucleus may have been no more than the length of two football fields.

The disintegrating ATLAS comet is currently located inside the orbit of Mars, at a distance of approximately 145 million kilometres from Earth when the latest Hubble observations were taken. The comet will make its closest approach to Earth on 23 May at a distance of approximately 115 million kilometres, and eight days later it will skirt within 37 million kilometres of the Sun.
You can view an animation of Hubble's observations on YouTube.
Science

Scientists Create Glowing Plants Using Mushroom Genes (theguardian.com) 66

An anonymous reader quotes a report from The Guardian: Emitting an eerie green glow, they look like foliage from a retro computer game, but in fact they are light-emitting plants produced in a laboratory. Researchers say the glowing greenery could not only add an unusual dimension to home decor but also open up a fresh way for scientists to explore the inner workings of plants. "In the future this technology can be used to visualize activities of different hormones inside the plants over the lifetime of the plant in different tissues, absolutely non-invasively. It can also be used to monitor plant responses to various stresses and changes in the environment, such as drought or wounding by herbivores," said Dr Karen Sarkisyan, the CEO of Planta, the startup that led the work, and a researcher at Imperial College London. "We really hope to bring this to the market in a few years from now, once we make them a bit brighter, once we make the ornamental plants with this new technology, and once of course they pass all the existing safety regulations," he added.

Writing in the journal Nature Biotechnology, Sarkisyan and a team of colleagues based in Russia and Austria report how they inserted four genes from a bioluminescent mushroom called Neonothopanus nambi into the DNA of tobacco plants. These genes relate to enzymes that convert caffeic acid, through a series of steps, into a luciferin that emits energy as light, before turning the resulting substance back into caffeic acid. The upshot is plants that glow with a greenish hue visible to the naked eye. "They glow both in the dark and in the daylight," said Sarkisyan, adding that the light appeared to be 10 times brighter than that produced by using bacterial genes. The team found the site of the luminescence changed as the plants grew, and luminescence generally decreased as leaves aged and increased where leaves became damaged. Flowers produced the most luminescence, the team report.

Software

Half of Americans Won't Trust Contact-Tracing Apps, New Poll Finds (arstechnica.com) 221

Before life can safely return to normalcy, we'll need an enormous increase in our ability to perform contact tracing -- identifying and contacting everyone who's been in contact with a person infected with COVID-19 so that they in turn can hunker down in quarantine and avoid infecting others. But, as Ars Technica reports, there are two huge problems with the massive contact-tracing platform that Google and Apple are working on. "First, billions of phones won't be able to use the tech," reports Ars. "And second: even among those who could, a solid half of Americans would refuse to because they don't trust insurers or tech companies with their health data." From the report: The 82 percent of US adults who have smartphones are exactly split on the issue, according to poll data released today by The Washington Post and University of Maryland. Half of the poll respondents said they probably or definitely would use a contact-tracing app, and the remaining half said they probably or definitely would not. While a majority of respondents (57 percent) expressed a reasonable amount of trust in public health agencies, less than half (47 percent) said they trust health insurance firms, and only 43 percent said they trust tech firms such as Google or Apple. Overall, the poll indicates that only 41 percent of American adults have both the technological capacity and the will to use a contact-tracing app. That's a problem, as research suggests that digital tracing would have to reach about 60 percent of the population to be most effective.
Education

Some School Districts Plan To End the Year Early, Call Remote Learning Too Tough (wsj.com) 93

An anonymous reader quotes a report from The Wall Street Journal: Some districts are giving up on remote learning and ending the academic year early, after concluding that it was too cumbersome for teachers, students and parents. Washington, D.C., as well as parts of Georgia, Texas and elsewhere plan to end a week to several weeks early. Schools have struggled to launch remote learning for more than 50 million children across the country during the coronavirus pandemic in the largest experiment in remote learning ever. Among the issues they've encountered, not all students have internet access or have parents available to help, causing concerns about inequity. As a result, many districts haven't required schoolwork be completed or graded. Student participation, when schools are even able to measure it, has often been below regular attendance level. When schools do eventually reopen, they'll look vastly different than they did before. There may be more scheduled days home, more online learning, and lots of hand-washing.

In parts of China, where life is slowly returning to normalcy, an elementary school in Yangzheng had students design hats that measure 1 meter (3.2 feet) across as a lesson in coronavirus safety practices. "We're advocating students to wear a one-meter hat and maintain one meter's distance," the Zhejiang Daily newspaper quoted Hong Feng, the school's principal, as saying as the kids returned to school this week for the first time in several months.

"Along with teaching the students about social distancing, the headgear is giving the kids a history lesson: The hats resemble those worn during the Song Dynasty, which ruled China between 960 and 1279," adds CNET. "The long horizontal plumes on Song Dynasty toppers were supposedly to prevent officials from conspiring sotto voce with one another while at court -- so social distancing was in fact their original function," Eileen Chengyin Chow, a Duke University professor of Asian and Middle Eastern studies, explained on Twitter.
Medicine

Gilead Says Critical Study of Covid-19 Drug Shows Patients Are Responding To Treatment (statnews.com) 54

A government-run study of Gilead's remdesivir, perhaps the most closely watched experimental drug to treat the novel coronavirus, showed that the medicine is effective against Covid-19, the disease caused by the virus. From a report: Gilead made the announcement in a statement Wednesday, stating: "We understand that the trial has met its primary endpoint." The company said that the National Institute of Allergy and Infectious Diseases, which is conducting the study, will provide data at an upcoming briefing. The finding -- although difficult to fully characterize without any data for the study -- would represent the first treatment shown to improve outcomes in patients infected with the virus that put the global economy in a standstill and killed at least 218,000 people worldwide.

During an appearance alongside President Trump in the Oval Office, Anthony Fauci, the director of NIAID, said the data are a "very important proof of concept" and that there was reason for optimism, but cautioned the data were not a "knockout." Over the past few weeks, there have been conflicting reports about the potential benefit of remdesivir, a drug that was previously tried in Ebola. As previously reported by STAT, an early peek at Gilead's study in severe Covid-19 patients, based on data from a trial at a Chicago hospital, suggested patients were doing better than expected on remdesivir. Days later, a summary of results from a study in China showed that patients on the drug did not improve more than those in a control group.

Medicine

Virus Likely To Keep Coming Back Each Year, Say Top Chinese Scientists (bloomberg.com) 187

Chinese scientists say the novel coronavirus will not be eradicated, adding to a growing consensus around the world that the pathogen will likely return in waves like the flu. From a report: It's unlikely the new virus will disappear the way its close cousin SARS did 17 years ago, as it infects some people without causing obvious symptoms like fever. This group of so-called asymptomatic carriers makes it hard to fully contain transmission as they can spread the virus undetected, a group of Chinese viral and medical researchers told reporters in Beijing at a briefing Monday. With SARS, those infected became seriously ill. Once they were quarantined from others, the virus stopped spreading. In contrast, China is still finding dozens of asymptomatic cases of the coronavirus every day despite bringing its epidemic under control. "This is very likely to be an epidemic that co-exists with humans for a long time, becomes seasonal and is sustained within human bodies," said Jin Qi, director of the Institute of Pathogen Biology at China's top.

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